Carbohydrate-based Vaccines
This course will be held on 8 and 9 November 2010in the Netherlands, at the Regardz Berghotel, Amersfoort.
Course Introduction and Aims
Many important diseases are caused by bacteria expressing cell surface carbohydrates, and where antibody responses against these glycans are protective against disease. This offers a mechanism to create protective immunity, which is now being widely exploited.
This intensive post-experience course covers the development of polysaccharide and glycoconjugate vaccines, their manufacture and quality control, and those factors considered crucial for an effective product. The molecular mechanisms by which these vaccines work and clinical trial and post licensure monitoring of their effects will also be covered.
Who should attend
The course is designed primarily for industrial and academic scientists engaged in vaccine development, and particularly in development, production, purification, characterisation, quality control, and also for professionals involved in the licensing and regulation of products of this type.
Course Topics
- Diseases caused by bacteria possessing a glycocalyx
- Purified polysaccharide vaccines
- Introduction to conjugate vaccines
- Conjugation chemistries
- Characterisation and Quality control of glycoconjugate vaccines
- Serological responses to glycoconjugate and polysaccharide vaccines
- Mechanisms of immunogenicity of polysaccharide and glycoconjugate vaccines
- Epidemiology and vaccine efficacy - lessons from clinical trials and post-marketing surveillance
- Future prospects
Tutorial team
The tutors, who will be in attendance throughout the course, bring to bear a wealth of varied teaching, research and industrial experience:
- Chris Jones, Ph.D is Head of the Laboratory of Molecular Structure at the National Institute for Biological Standards and Control (NIBSC), South Mimms, UK.
- Chris Jones profile
- Ian Feavers is Head of the Division of Bacteriology at NIBSC, South Mimms, UK.
- Ian Feavers profile
Fees, venue and terms
The fully inclusive registration and course fee is €950 and the course is limited to the first 25 applicants whose registration has been confirmed.
Please register using the on-line registration form below and also read details of our privacy policy.
Both course and accommodation will be at the pleasant 4 star Regardz Berghotel, address Utrechtseweg 225, 3818 EG, Amersfoort, the Netherlands; telephone 0031 33422 4222. Amersfoort can easily be reached by train from Schiphol airport (a train leaves every 30 minutes and the journey takes 45 minutes).
The course fee includes registration, accommodation for one night (8 November 2010), dinner, continental breakfast and two lunches, all tuition and a comprehensive course manual. The course will begin at 10.00am on 8 November and end at approximately 16.30pm on 9 November. For more information please e-mail the BioUpdate course administrator, David Sylvester, at admin@bioup.com.
Those who would like to stay in the hotel the night before the start of the course, 7 November, should make reservations directly with the hotel, tel: 0031 33422 4290, (Monday to Friday 0900 to 1700, Netherlands time), Email: berghotel@regardz.nl, and mention the BioUpdate Foundation. (For this purpose BioUpdate has reserved a block of rooms at €89 per night.) The hotel bill for such a room (7 November) must be settled independently.
Please complete this on-line Course Registration Form
Contact Information
For more information or if you have any questions regarding this form or payment options please e-mail the BioUpdate course administrator at: admin@bioup.com